WHY IS THIS MEDICATION PRESCRIBED?

Why is this medication prescribed?

Why is this medication prescribed?

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Tofacitinib is used alone or with other medications to treat rheumatoid arthritis (condition in which the body attacks its own joints causing pain, swelling, and loss of function) in adults who are unable to take or did not respond to one or more tumor necrosis factor (TNF) inhibitor medication(s). It is also used to treat psoriatic arthritis (a condition that causes joint pain and swelling and scales on the skin) in adults who are unable to take or did not respond to or Tofacitinib 5 mg (Tofacent) one or more TNF inhibitor medication(s). Tofacitinib is used to treat ulcerative colitis (a condition which causes swelling and sores in the lining of the colon [large intestine] and rectum) in adults who are unable to take or who did not respond to one or more TNF inhibitor medication(s). It is also used to treat polyarticular juvenile idiopathic arthritis (PJIA; a type of childhood arthritis that affects five or more joints during the first six months of the condition, causing pain, swelling, and loss of function) in children 2 years and older who are unable to take or who did not respond to one or more TNF inhibitor medication(s). Tofacitinib is in a class of medications called Janus kinase (JAK) inhibitors. It works by decreasing the activity of the immune system.

How should this medicine be used?
Tofacitinib comes as a tablet, an extended-release (long-acting) tablet, and as an oral solution (liquid) to take by mouth. For the treatment of ulcerative colitis, rheumatoid arthritis, or psoriatic arthritis, the tablet is usually taken twice daily with or without food and the extended-release tablet is usually taken once daily with or without food. For the treatment of polyarticular course juvenile idiopathic arthritis, the tablet or the oral solution is usually taken twice daily with or without food. Take tofacitinib at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take tofacitinib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Swallow the extended-release tablets whole; do not split, chew, or crush them.

Always use the oral dosing syringe that comes with tofacitinib solution to measure your dose. Talk to your doctor or pharmacist if you have questions about how to measure your dose of tofacitinib solution.

If you or your child are taking tofacitinib oral solution, ask your pharmacist or doctor for a copy of the manufacturer's instructions for use. Carefully read these instructions.

Your doctor may need to decrease your dose or stop your treatment if you experience certain severe side effects. Be sure to tell your doctor how you are feeling during your treatment.

 

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